Abstract
We report a case of eosinophilic gastroenteritis. A 69-year-old man had been taking prednisolone 5 mg/day for asthma. Cholecystectomy and bile duct resection was performed for gall bladder cancer in October 2007. After surgery, fever, upper abdominal pain, vomiting, leukocytosis and liver dysfunction were frequently observed, and thought to be due to cholangitis. Symptoms were observed about once a month and urticarial lesion and facial flush were also observed. Symptoms improved in a few hours or half a day. Symptoms then occurred more frequently and severely. The number of peripheral eosinophilia and IgE level also increased. Abdominal computed tomography (CT) scan showed edema of the gastric wall, and gastric biopsy specimens showed massive eosinophilic infiltration. We had already guessed that this was a case of gall bladder cancer before the operation, because upper abdominal pain also occurred after the operation. We eventually diagnosed eosinophilic gastroenteritis, and performed pulse steroid therapy, and the symptoms improved dramatically. We were able to reduce prednisolone without recurrence.