Abstract
A 76-year-old woman underwent mastectomy and axially lymph node dissection for primary right breast cancer in May 2003. Histological examination revealed invasive ductal carcinoma (papillotubular type), ER 71%, PgR 33%, HER2 (-), pT4bN1M0, and Stage IIIB. After adjuvant chemotherapy with CMF regimen and PMRT CT scan revealed mediastinal, cervical and abdominal lymph node metastases in May 2005. Hormone therapy (ANA→LET→TAM) was thus started. We found type 2 tumor at the level of the mid-esophagus in October 2010. Endoscopic biopsy revealed Group V, ER (+), HER2 (+), and so esophageal metastasis of breast cancer was diagnosed. Although chemotherapy (trastuzumab + docetaxel → trastuzumab + vinorelbine → FEC regimen) was carried out, she had had recurrent bouts of contracting pneumonia since August 2000. Esophagobronchial fistula had been formed at the esophageal metastasis, for that an esophageal covered stent was placed there. No pneumonia has occurred since 2 months after the stenting and she is doing well for 8 months by receiving trastuzumab + S-1 regimen.
