Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association)
Online ISSN : 1882-5133
Print ISSN : 1345-2843
ISSN-L : 1345-2843
Case Reports
A Case Report of Pathologic Complete Response with Neoadjuvant Chemo (UFT+UZEL) -Radiation (IMRT) for Locally Advanced Rectal Cancer Invading other Organs
Kohei NISHIGAMI, Hisashi TARAO, Tomohito YAMAGUCHI, Kiyotaka YAMAGUCHI, Hiroyuki KAWAMI, Takashi TANAKA
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2013 Volume 74 Issue 7 Pages 1962-1967

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Abstract
A 65-year-old man presented to a local hospital because of diarrhea and abdominal pain. Following colonoscopy and abdominal CT, rectal cancer, ileus and a retoroperitoneal abscess were diagnosed. He was referred to our hospital. We performed percutaneous dranage for the retroperitonial abscess, followed by only transient colostomy because the rectal cancer had invaded the bladder and the left wall of pelvis, and his general condition was poor due to the abscess and ileus. A tolal of 40 Grey IMRT (intensity-modulated radiation therapy) with UFT + UZEL chemotherapy for 28 days was given. After the therapy, CT, FDG-PET and colonoscopy revealed remarkable shrinkage of the tumor. High anterior resection of the rectum with D3 lymphadenectomy and partial resection of the bladder were then performed. Histopathological examination showed complete regression of the tumor, rated as Grade 3, pathologic complete response (pCR).
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© 2013 Japan Surgical Association
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