Abstract
A 19-year-old male had been diagnosed as having ulcerative colitis when he was a 14-year-old, but he had not been treated with salazosulfapyridine. He developed constipation and fever. On CT, wall thickness was found in the transverse colon ; a stenosis in the transverse colon was identified on barium enema studies and colonoscopy. After 2 months of conservative therapy, he underwent a laparoscopic subtotal colectomy. The resected specimen had inflammatory polyposis in the ascending and transverse colon. On pathology, crypts with regenerative-hyperplastic changes, inflammatory cellular infiltration, crypt abscesses in the lamina propia, many lymph follicles and fibrous changes between the submucosa and the subserosa were noted. There was no evidence of a non-caseous epithlioid granuloma. Therefore, neither ulcerative colitis nor Crohn's disease could be diagnosed. Thus, the patient was diagnosed as having indeterminate colitis.