Abstract
We encountered a rare case of well-differentiated duodenal adenocarcinoma with scirrhous stroma. An 85-year-old man was admitted due to vomiting. Abdominal CT showed thickening of the duodenal wall. Barium enema studies revealed stenosis of the duodenal bulb. Endoscopic examination revealed an irregular sore with a small granule on the mucous membrane of the duodenal bulb. The biopsy specimen from the region was diagnosed as Group IV. Preoperative examination disclosed a tumor confined to the duodenal wall but no lymph node metastasis, and we performed a pancreatoduodenectomy. The resected specimen contained a 60×50-mm Borrmann type 5 tumor in the duodenum. Pathology revealed scirrhous stroma of well-differentiated adenocarcinoma invading the serosa with lymph node metastasis.