Abstract
Angiosarcoma induced by radiation lacks characteristic clinical and imaging findings, and its definitive diagnosis is considered difficult, even with cytology and needle biopsy. No established treatments exist, and surgical resection is the basic treatment, with the prognosis generally being poor. The present patient was a woman who was 78-year-old at the time of diagnosis of angiosarcoma. In 2007, she underwent left partial mastectomy and sentinel lymph node biopsy for left breast cancer. Postoperatively, she received endocrine therapy following radiation for the conserved breast. In 2011, she underwent a skin biopsy at a previous clinic after a skin tumor was detected in the left breast. After the biopsy failed to yield a diagnosis, she was referred to our hospital. Considering the possibility of angiosarcoma induced by radiation or skin recurrence, left mastectomy and axillary lymph node sampling were performed. On histopathological examination, the diagnosis was angiosarcoma. In addition, the tumor had been completely resected. Given the clinical course, radiation-induced angiosarcoma was diagnosed. The patient was followed without treatment, but right knee metastasis and pleural dissemination developed one year postoperatively, and the patient died one month later.
