Abstract
Retroperitoneal leiomyosarcoma is a rare tumor of the soft tissue and metastasizes relatively early after the resection of primary lesion. We experienced a case of retroperitoneal leiomyosarcoma which metastasized to the lung six years after the resection of the primary lesion.
A 76-year-old woman who had undergone surgical resection of a 4.5-cm right retroperitoneal leiomyosarcoma 7 years earlier consulted us due to a nodule in the right lung detected on a chest computed tomography scan. It appeared as a tumor of 4 mm in diameter 6 years after the primary operation and gradually. We performed a video-assisted thoracoscopic surgery for the diagnosis and therapy and resected the tumor of 8 mm in diameter in the right lower lobe. Histopathological examination revealed growth of pleomorphic smooth muscle cells which were immunohistochemically positive for α-smooth muscle actin and desmin. Therefore pulmonary metastasis of the retroperitoneal leiomyosarcoma was diagnosed. No recurrence has been found for 6 months after the pulmonary resection. Pulmonary metastasis of retroperitoneal leiomyosarcoma with a long disease free interval is rare. There are various clinical courses for leiomyosarcoma and further recurrence may occur in the future. Follow-up observation would be mandatory.
