Abstract
Surgical intervention is recommended for severe Clostridium difficile-associated disease (CDAD), and the mortality rate is high, at 24-80% in operated patients. An 82-year-old man developed diarrhea after treatment for community-acquired pneumonia with antibiotics. He was then diagnosed with pseudomembranous enteritis and was prescribed metronidazole, but the patient was admitted to our hospital because of severe abdominal pain and distension. Bloody bowel discharge was seen after hospitalization, white blood cell count was increased, and the patient met the criteria for SIRS with megacolon on computed tomography. Pseudomembranous enteritis was seriously worsening compared to the above, and we decided to perform emergency surgery. Left colectomy was performed and an artificial anus was prepared with transverse colon. Septic shock and Disseminated intravascular coagulation (DIC) developed transiently after surgery, but he recovered and achieved an excellent prognosis with some anti-DIC treatments.
