Abstract
Herein, we report a case of a leiomyosarcoma arising from the left ovarian vein, which is extremely rare. A 65-year-old woman was referred to our hospital because of a palpable mass in her left lower abdomen. The pre-operative diagnosis was left ovarian cancer or leiomyosarcoma of the ovarian vein. The operative findings revealed that the ovary was obviously normal and the left ovarian vein was involved by the mass. We resected the mass and the left ovary. Histopathological findings revealed that the tumor was connected to the left ovarian vein, and immunohistochemical staining demonstrated that the tumor cells expressed smooth muscle cell antigens, such as smooth muscle actin and desmin, but they showed no staining for S-100, CD34, or c-kit. As a result, a diagnosis of leiomyosarcoma was made. The postoperative course was uneventful and the patient has had no recurrence after 6 months.