Colonic Metastasis from Biliary Tract Cancer Manifesting as Diverticular Perforation

Abstract

We performed right hemicolectomy for diverticular perforation in a 65-year-old man who had undergone pancreaticoduodenectomy for bile duct cancer three years earlier. Macroscopic examination of the resected specimen showed diverticular perforation and irregularity of the colon on the anal side of the diverticulum. Histopathological examination showed a tumor infiltrating the submucosa and muscularis propria. The expression pattern of cytokeratin and Cdx2 on immunohistochemical examination was consistent with bile duct cancer origin rather than colon cancer origin, and we diagnosed the patient as having developed colonic metastasis from bile duct cancer.