Abstract
A 66-year-old man was admitted for further examination of multiple hepatic tumors of segment 8 detected on abdominal computed tomography performed for treatment of acute prostatitis. Tumor 1, 1.5 cm in diameter, was located at the most cranial side. Tumor 2, 6 cm in diameter, had invaded the diaphragm. Tumor 3 consisted of cystic and nodular lesions. The cyst was about 4 cm in diameter and accompanied by distal bile duct distention. A 2-cm nodular lesion had invaded the lumen of the cystic lesion. Although abdominal imaging studies suggested hepatocellular carcinoma (HCC), cystadenocarcinoma and intraductal papillary neoplasm of the bile duct remained in the differential diagnoses. We performed right hemihepatectomy. Histopathological findings revealed that tumor 2 was the main lesion and tumors 1 and 3 were intrahepatic metastases. HCC with invasion of a simple hepatic cyst is very rare, and there have been no previous reports of similar pathological conditions.