Abstract
A 50-year-old woman underwent curative resection of sigmoid colon cancer (Type 2, 70×55 mm) with partial resection of the bladder. Histopathological examination revealed moderately differentiated tubular adenocarcinoma invading the bladder (SI), lymph node metastasis (N2), lymphatic invasion (ly1), and venous invasion (v1). Postoperatively, she had received adjuvant chemotherapy (mFOLFOX6). Fourteen months after the operation, she was brought to a hospital with seizures. Brain CT and MRI revealed a mass lesion in the right parietal lobe, diagnosed as a solitary brain metastasis. Chest-abdominal CT showed no metastases to the liver, lungs, or bone. She underwent Cyber Knife radio therapy. Following radio therapy, she received mFOLFOX6. Brain metastasis from colorectal cancer typically appears with multiple brain lesions and/or metastases to other organs and carries a poor prognosis. In the case of solitary brain metastasis treated surgically or by radio therapy, long-term survival can be expected.
