Abstract
A 74-year-old woman had undergone hepatectomy for a ruptured hepatocellular carcinoma (HCC) six years previously, and upper gastrointestinal endoscopy showed gastric submucosal tumor with no symptoms. The tumor was 2.1×1.7 cm in size. According to the endoscopic excisional needle biopsy, the preoperative diagnosis was gastrointestinal stromal tumor (GIST), epithelioid type, on the basis of KIT negativity and discovered on GIST-1 positivity on immunohistochemical staining. Conversely, the pathological diagnosis was considered to be peritoneal metastasis of HCC. Although peritoneal metastasis of HCC is rare, accounting for only 0.32% of all cases of HCC recurrence, the pattern of metastasis could be solitary or tardive. Early diagnosis of peritoneal metastasis is rare and difficult. We present this case with a review of the literature.