Abstract
A 44-year-old woman visited our hospital because of a 1.5 year history of severe abdominal distension. When she was first seen, her upper half of the body showed remarkable emaciation and the abdomen was seriously bulging. An abdominal CT scan showed a giant tumor occupying almost the entire abdominal cavity. She was operated on under a diagnosis of retroperitoneal liposarcoma. At laparotomy, the tumor had displaced abdominal organs such as the small intestine, colon, liver, and stomach, and it surrounded the pancreatic body and tail. We radically resected the tumor with the spleen and pancreatic tail. The resected tumor was 63 × 41cm in diameter and weighed 24.5kg. The histopathological diagnosis was well-differentiated liposarcoma. Recurrence was detected in the peripancreatic retroperitonium and the surface of the liver 6 months after the first surgery, and the tumors were resected. Three months later, another abdominal CT scan revealed multiple recurrences in the liver and we started systemic chemotherapy. The multiple recurrences progressed and the patient died 2 years and 7 months after the first surgery. Here we report the case of a giant retroperitoneal liposarcoma exceeding 20kg in weight, and discuss the contiguous organ resection and the systemic chemotherapy.