Abstract
A 39-year-old man who came to our hospital because of an epigastric mass with pain was found to have a solid tumor in the lateral segment of liver on abdominal ultrasonography and CT scan. Blood examination showed a slight rise in inflammatory marker, but hepatic function was normal. Hepatitis virus were negative and tumor markers were within normal ranges. Abdominal CT and MRI scans visualized it as an ischemic tumor. As the tumor was associated with pain and rupture of the tumor was considered probable, left hepatectomy was performed. Histopathology revealed solid proliferation of spindle-shaped cells. On immunohistochemistry, the tumor cells were positive for Vimentin and negative for epithelial markers such as CK, hepatocyte, and CK7. The tumor cells were also negative for S100, smooth muscle actin (SMA), CD34, CD68, and desmin. Undifferentiated sarcoma was thus diagnosed. The patient is alive and has been free from disease recurrence, as of one year and 6 months after the operation.
The disease is a rare malignant mesenchymal tumor in infants and children. It is extremely rare in adults. We present a case of undifferentiated hepatic sarcoma affected a 39-year-old man, with a review of the literature.
