Abstract
Spindle cell carcinoma of the breast is a relatively rare tumor. In most cases, this breast tumor exhibits the triple-negative phenotype, namely, ER-negative, PgR-negative and HER2-negative. We report a case of chemotherapy-resistant spindle cell carcinoma of the breast. The patient was a 75-year-old female presenting with the chief complaint of a mass in the right breast. Core needle biopsy revealed findings consistent with the diagnosis of spindle-cell carcinoma. Modified radical mastectomy with sentinel lymph node biopsy was performed. The disease was classified as pT3pN0(SLN)pMX according to the TNM classification (UICC). The tumor subtype was TNBC. Adjuvant chemotherapy was administered with cyclophosphamide+dexorubicin (AC) followed by docetaxel. One month after the completion of chemotherapy, the patient developed pulmonary metastasis, for which neither bevacizumab+paclitaxel nor eribulin mesylate proved effective. Unfortunately, the patient died nine months after the operation.
