Abstract
A 49-year-old man with a 10-year history of Crohn's disease presented with abdominal pain after meals. Computed tomographic examination showed almost complete obstruction of the ileocecum by a large intraluminal mass. Colonofiberscopy findings showed a mass consisting of numerous filiform polyps, and subsequently, a laparoscopy-assisted right colectomy was performed. Filiform polyps were located from the cecum to the transverse colon, and were not present in the ileum of the resected specimen. Histological findings of the mass confirmed the clinical diagnosis of localized giant inflammatory polyposis, consisting of regenerated epithelium and inflammatory stroma with lymphoid hyperplasia. Epithelioid granulomas including multinucleated giant cells were seen. There was no evidence of dysplasia or malignancy. Giant inflammatory polyposis may be associated with Crohn's disease, but is a rare cause of colonic obstruction, while intestinal obstruction in Crohn's disease is one of the common complications, requiring surgery, usually shows ulceration and constriction with fibrosis.
