Abstract
A 70-year-old man was referred to our hospital with jaundice. Contrast-enhanced computed tomography revealed a mass lesion in the bile duct. The patient was diagnosed with bile duct cancer, and subtotal stomach-preserving pancreatoduodenectomy combined with D2 lymph node dissection was performed. The pathological and immunohistochemical diagnosis was small cell carcinoma with adenocarcinoma (Bd, 2.3×1.5 cm, flat-infiltrating type, ss, INFγ, ly1, v1, pHinf0, pGinf0, pPanc0, pDu0, pPV0, pA0, pHM0, pDM0, pEM0 T2, N0, H0, P0, M0 Stage IB). The patient is alive without recurrent disease 16 months after the operation, without any adjuvant chemotherapy. Small cell carcinoma of the bile duct is an extremely rare neoplasm. The treatment strategy for this disease has not yet been established, but curative surgery plays an important role.
