Abstract
A 73-year-old woman was admitted to our hospital in 2009 with complaints of anal pain and hematochezia. She had undergone hysterectomy for uterine body cancer in 1998, while she was diagnosed with branch-duct intraductal papillary mucinous neoplasm (IPMN) of the head of the pancreas. Subsequently, she underwent bilateral partial mastectomies for breast cancers in 2005 and subtotal distal pancreatectomy for cancer of the pancreatic body in 2006. As the IPMN displayed no signs of malignancy, resection was not performed. This time, anoscopy detected an ulcerating tumor in the anal canal and histological examination revealed the tumor was adenocarcinoma. Several lymph nodes were depicted in the left inguinal region on computed tomography. The IPMN in the remnant pancreas showed no changes. The patient underwent abdominoperineal rectal amputation, but died of recurrence 9 months after surgery. IPMT of the pancreas is well known to coincide with cancer of other organs, but cases with multiple primary cancers are rare. The prognosis of such cases of IPMN with multiple cancers often depends on the malignant behavior of cancers in other organs, and careful follow-up is therefore necessary for patients with IPMN.
