Abstract
Adenosquamous carcinoma of the extrahepatic biliary tract is a relatively rare disease, and in general, has a poor prognosis. A 73-year-old man with jaundice was referred to our hospital for further examination and possible surgery. Contrast-enhanced abdominal CT showed dilatation of the intra and extrahepatic bile ducts and a contrast-enhancing tumor about 15 mm in diameter in the distal extrahepatic bile duct. ERCP showed the tumor in the distal extrahepatic bile duct and a biopsy revealed the diagnosis of adenosquamous carcinoma of the bile duct, as the tumor contained a mixture of both adenocarcinoma and squamous cell carcinoma components. Subtotal stomach-preserving pancreaticoduodenectomy was performed. Histopathology of the resected specimen confirmed the diagnosis of adenosquamous carcinoma of the bile duct based on the presence of both adenocarcinoma and squamous cell carcinoma components in the tumor. Metastases to the liver were identified 3 months after the surgery and the patient died of acute respiratory failure complicating aspiration pneumonia 6 months after the surgery.
