Abstract
[Objective]
We analyzed the risk factors for the development of postoperative complications following laparoscopic cholecystectomy for acute cholecystitis.
[Methods]
The participants comprised 289 patients with acute cholecystitis who underwent laparoscopic cholecystectomy, including those needing conversion to open surgery, from 2010 to 2014 at our hospital. We defined postoperative complications according to the Clavien-Dindo classification.
[Result]
Postoperative complications occurred in 24 patients (8.3%). Univariate analysis identified the risk factors for postoperative complications as an interval of more than 72 h from symptom onset to surgery, cholecystitis severity categorized as greater than mild according to the classification in Tokyo guidelines 2013 (TG13), heavy intraoperative blood loss and elevated serum C-reactive protein (CRP) values. Multivariate analysis identified only intraoperative blood loss ≥ 223 g and serum CRP value ≥ 12.7 mg/dl among the above-listed factors as significant risk factors for the development of postoperative complications.
[Conclusion]
Both univariate and multivariate analyses in our study identified heavy intraoperative blood loss and elevated serum CRP as risk factors for the development of postoperative complications.
