Abstract
A 75-year-old woman had been referred to a hospital for detailed examination of a thyroid tumor at the age of 53 years. She was diagnosed as having multiple endocrine neoplasia type 2A with medullary thyroid carcinoma (MTC) and bilateral adrenal pheochromocytomas, and had been treated by total thyroidectomy and bilateral subtotal adrenalectomy. She showed no signs of recurrence for the subsequent 20 years, and was referred to the endocrinology department of our hospital. Abdominal USG performed 21 years after the first surgery revealed the presence of a tumor in the liver (S3). Contrast-enhanced abdominal CT showed a well-stained hypervascular tumor measuring 20 mm in diameter with calcification, which was found to be associated with elevation of the plasma calcitonin concentration.
Consequently, she was diagnosed as having hepatic metastasis from MTC. We performed lateral hepatic segmentectomy at our department ; there were 2 tumors and the histopathological diagnosis was metastasis from MTC. Currently, 34 months after the hepatic resection, the patient remains alive without recurrence. We describe this rare case of metachronous hepatic metastasis from MTC treated by radical resection, with a review of the relevant literature.
