Abstract
The patient was a 64-year-old woman who underwent a living renal transplant for chronic renal insufficiency 20 years ago, and received continuous treatment with immunosuppressants. This time we found an irregular tumor in her right breast, and diagnosed breast cancer after intensive examination. We performed a breast lumpectomy and a sentinel lymph node biopsy. The histopathological diagnosis was HER2-positive breast cancer accompanied by highly-infiltrative tumor lymphocytes. As a post-operative adjuvant therapy, we administered weekly paclitaxel and trastuzumab treatment for 12 cycles. In the 9 years since the operation, the patient has experienced event-free survival. With the advancement of immunosuppressant therapy, the long-term prognosis for transplantation patients has improved, but the frequency of malignant tumor occurrence after transplantation has increased. We experienced a case who had good prognosis with administering post-operative adjuvant chemotherapy for a breast cancer that occurred after a living renal transplant. We hereby report the case with a review of the literature.
