Abstract
It is extremely rare that benign fibrous histiocytomas (BFH) arise in the intestine. We have experienced a case of BFH of the duodenum which was surgically resected. The case involved a 60-year-old man complaining of abdominal pain. Esophagogastroduodenoscopy and CT scan revealed a submucosal tumor at the duodenal bulb. Endoscopic ultrasound-guided fine needle aspiration cytology suggested a questionable histiocytic tumor. A possibility of malignant disease could not be ruled out because he was symptomatic, and distal gastrectomy, lymph node dissection, and Roux-en-Y reconstruction were performed. Histopathology did not show any findings suggestive of apparent malignancy but accumulation of histiocytes. A variety of immunohistochemical studies showed diffusely positive reactions for CD68/CD163/CD31. BFH of the duodenum was thus diagnosed. No recurrence has occurred as of 18 months after the operation.
As clinical cases of BFH arisen in the intestine have extremely rarely been reported so far, our case is presented here with a review of the literature.
