Abstract
Here, we describe a case of mucinous adenocarcinoma of the distal bile duct. A 67-year-old man was referred to our clinic with liver dysfunction. Although he was asymptomatic, computed tomography revealed bile duct dilation and a mass in the distal bile duct. Following endoscopic biliary biopsy through the duodenal papilla Vateri, which revealed adenocarcinoma, he was diagnosed with cancer of the distal bile duct. A subtotal stomach preserving pancreatoduodenectomy was performed for a cT2, cN0, cM0 tumor. The pathological diagnosis was poorly differentiated mucinous adenocarcinoma, and the discovery of multiple lymph node metastases indicated stage pT3a, pN1, M0, II B disease. Although his postoperative course was uneventful, he died of a cancer recurrence 10 months after surgery. We further address the rarity of mucinous adenocarcinoma of the distal bile duct through a review of the literature.