Abstract
We report a surgically resected case of gastric eosinophilic granuloma caused by parasitic infection that was preoperatively diagnosed as a GIST. A 65-year-old woman who had received Helicobacter pylori eradication therapy was found by gastrointestinal endoscopy to have a submucosal tumor with an ulcer in the greater curvature of the middle part of the stomach. Abdominal CT showed a gastric submucosal tumor measuring 15 mm in diameter with extraluminal growth. Endoscopic ultrasonography showed a hypoechoic mass in the muscular layer of the gastric wall. Endoscopic ultrasonography-guided fine-needle aspiration biopsy specimens were not sufficient to obtain a diagnosis. The patient was preoperatively diagnosed as having a GIST and laparoscopic local resection of the stomach was performed. Microscopic examination of the resected specimen showed a worm-like structure in the submucosal layer surrounded by an eosinophilic granuloma. Gastric eosinophilic granuloma caused by parasitic infection is rare and is often difficult to diagnose preoperatively. This case serves to emphasize that the possibility of this disease should be kept in mind in the differential diagnosis of gastric submucosal tumors.