Abstract
There is no proven therapy for the distant metastasis of malignant phyllodes tumors. We report a case wherein radiotherapy was effective for metastases of a malignant phyllodes tumor in multiple organs. Case : A 27-year-old woman noticed a left breast mass. After observation for 5 years, she underwent lumpectomy because of the increasing size of the mass. She was diagnosed with giant fibroadenoma (14 cm). She presented with local recurrence and underwent resection 6 times sequentially. The pathological diagnosis was fibroadenoma based on the first resected specimen but was malignant phyllodes tumor based on the latter. She had lung metastases in the lobes bilaterally at 56 years of age, followed by multiple metastases in various organs, such as the left pulmonary vein, right atrium, left gastrocnemius, small intestine, fingers, and others. She received radiotherapy for fetal metastases in the left pulmonary vein and right atrium of the heart for local control and palliative radiotherapy for the right gastrocnemius and fingers. These approaches of radiotherapy were effective in preventing fetal events, pain, and suffering for 10 months from the first detection of lung metastasis until her death.
