Abstract
Primary breast lymphoma (PBL) is an unusual disease, accounting for 0.4-0.5% of all breast malignancies. A very rare case of PBL of the right breast diagnosed simultaneously with invasive ductal carcinoma of the left breast is reported. A 62-year-old Japanese woman presented with a palpable tumor measuring 4.5 × 3.5 cm involving the right breast. The diagnosis was a suspected malignant breast tumor. A core needle biopsy (CNB) showed non-Hodgkin lymphoma. Magnetic resonance imaging (MRI) showed an enhanced mass in the right breast, and an enhanced focus in the left breast that was not seen on mammography and ultrasonography. The CNB of the left breast hypoechoic area was diagnosed as invasive ductal carcinoma. The patient underwent left mastectomy with sentinel lymph node biopsy and subsequently received chemotherapy (R-CHOP therapy).
Compared with breast cancer, PBL is a rare entity that should, nevertheless, be considered in the differential diagnosis of breast lesions. The coexistence of different breast malignancies presents a challenge in treatment strategy.
