Abstract
[Objectives] This study was made to clarify surgical outcomes of pancreaticoduodenectomy (PD) and postoperative long-term changes in nutritional indexes in elderly patients. [Subjects and methods] We enrolled a series of 100 patients undergone PD in our institution from 2009 to 2014. The subjects were divided into the elderly group comprising 20 patients of age 75 or over and the non-elderly group comprising 80 of age 74 or under. These two groups were compared for surgical outcomes and perioperative time-dependent changes in the total protein (TP), serum albumin (A1b), hemoglobin, number of lymphocytes, and Onodera's prognostic nutritional index (PNI). [Results] No statistically significant differences were noted in the surgical outcomes of PD between both groups. In the elderly group, significant decreases were noted in TP at postoperative 1 year, Alb at postoperative 3 months and one year, and PNI at postoperative one week and one year. A comparison between preoperative and postoperative 1 year values revealed no significant differences in TP, A1b, lymphocytes number, and PNI. [Conclusion] Surgical outcomes and postoperative changes in the nutritional indexes after PD in the elderly were almost comparable to those in non-elderly patients.
