Abstract
A 77 year old female patient presented to us with a history of abdominal pain and a palpable abdominal mass. Further examination revealed transverse colon cancer with extramural progression and multiple liver metastases. Accordingly, transverse colectomy was performed. Histopathological examination of the resected specimen revealed poorly differentiated adenocarcinoma with CK7-/CK20+. Despite treatment with three courses of mFOLFOX6 and bevacizumab following the colectomy, the patient died of progression of the liver metastases and the development of peritonitis carcinomatosa. This case report gives details about the very rarely encountered poorly differentiated adenocarcinoma of the transverse colon with extramural progression.