Abstract
A 35-year-old man complaining of epigastric pain received conservative treatment at a hospital, but no symptomatic remission was achieved. He visited another hospital two days later because lower abdominal pain, diarrhea, chill and a high fever of 38°C or higher developed. He was referred to our hospital with a suspected diagnosis of disseminated intravascular coagulation (DIC) from the blood analysis and biochemical findings. An abdominal CT scan performed at another hospital revealed swelling of the appendix with microcalcifications. However, there were no findings suggestive of perforation. DIC caused by acute appendicitis was diagnosed. We performed emergency operation. During the operation, we could not detect any findings of perforation of the appendix. The histopathological diagnosis was gangrenous appendicitis without demonstrable perforation. Postoperative intensive therapy provided improvement of general condition of the patient. He was discharged from our hospital on the postoperative day 11. Culture of the collected arterial blood yielded Eubacterium species. As non-perforative appendicitis with sepsis presented with DIC has rarely been reported, we present this case.