Abstract
A 28-year-old male, who had a history of severe acute pancreatitis (AP) and walled-off necrosis treated by percutaneous and endoscopic drainage, was admitted to our institute with ileus. At first, chronic intestinal pseudo-obstruction (CIPO) was suspected, but because cine MRI showed preserved peristaltic function of the small intestine, we made the diagnosis of chronic megacolon. Ileostomy was performed, and the patient is under follow-up at a nearby hospital. CIPO is characterized by peristaltic dysfunction of the small intestine and surgical treatment is often ineffective, whereas surgical treatment is highly effective for chronic megacolon. Therefore, differential diagnosis is very important. This is the first report of a case of chronic megacolon with peristaltic dysfunction secondary to AP reported from Japan.