A Case of Low-grade Adenosquamous Carcinoma of the Breast

Abstract

Low-grade adenosquamous carcinoma (LGASC) of the breast is a type of metaplastic carcinoma. Unlike other metaplastic carcinomas, LGASC exhibits a more favorable outcome. We present the case of a 43-year-old woman with a medical history of invasive ductal breast carcinoma 8 years before who was recently diagnosed as having a LGASC in the same breast and who underwent a surgical procedure. Simultaneously, on the other side of the breast, ductal carcinoma in situ was diagnosed and performed with mastectomy. Further therapy was not performed. BRCA1 mutation in association with LGASC has been reported. Thus, it may be important to consider the possibility of hereditary breast and ovarian cancer syndrome, and a surveillance program.