A Case of Malignant Transformation Arising in Rectal Endometriosis with Liver Metastasis

Abstract

Malignant transformation arising in intestinal endometriosis is extremely rare, and there is no report of simultaneous resection of intestinal endometrial adenocarcinoma with metastasis. We report a case of rectal endometrial adenocarcinoma with liver metastasis. The patient was a 53-year-old-woman. A tumorous lesion suspected of liver metastasis was observed in S6 and S8 on computed tomography for screening after a breast cancer surgery. Since adenocarcinoma was detected in a liver biopsy specimen, we performed colonoscopy and detected a type 1 tumor pathologically diagnosed as adenocarcinoma in the rectum. As a result of immunohistological staining, the hepatic lesions were not confirmed as metastases of breast cancer, and the possibility that the hepatic lesions were not liver metastasis of rectal cancer was also considered. However, high anterior resection and partial hepatic resection of S6 and S8 were performed after fully explaining the possibility. On histopathological examination, the patient was diagnosed with serous adenocarcinoma in rectal endometriosis with liver metastasis. Paclitaxel + carboplatin therapy was administered as adjuvant therapy, and the patient has survived without recurrence for 6 months.