A Case of Primary Duodenal Undifferentiated Pleomorphic Sarcoma

Abstract

A 69-year-old man was admitted to our hospital with a history of upper abdominal pain and anorexia. Upper gastrointestinal endoscopy revealed a tumor in the second portion of the duodenum. Biopsy revealed the diagnosis of undifferentiated pleomorphic sarcoma, and the patient was treated by subtotal stomach-preserving pancreatoduodenectomy. An abdominal CT performed 2.5 months after the surgery showed a local recurrence and liver metastases. Treatment was started with doxorubicin, however, the patient died 5.5 months after the operation. To the best of our knowledge, only 7 cases of duodenal undifferentiated pleomorphic sarcoma have been reported so far, including our case. This case is presented here, along with a discussion of the relevant literature.