A Case of Sporadic Multiple Non-functional Pancreatic Neuroendocrine Tumors with Lymph Node Metastasis

Abstract

The patient was a 33-year-old woman with unremarkable past medical history and family history. Abdominal ultrasonography during a routine medical checkup revealed a mass measuring 1 cm in diameter in the pancreatic body. The patient was asymptomatic, and her laboratory tests revealed normal levels of endocrine hormones and normal parathyroid function. Abdominal endoscopic ultrasound revealed 6 tumors varying in diameter from 2-20 mm in the body to the tail of the pancreas. The patient was diagnosed as having multiple non-functional pancreatic neuroendocrine tumors (pNET) and treated by distal pancreatectomy. The histopathological diagnosis was multiple NETs, G2, with lymph node metastasis. The patient remained relapse-free until our follow-up at 19 months. Herein, we report a rare case of sporadic multiple non-functional pNET, with a review of the literature.