A Case of Bladder Metastasis from Invasive Lobular Carcinoma of the Breast

Abstract

The patient was a 72-year-old woman who had been admitted to our hospital with a left breast mass at the age of 69. She was diagnosed with left breast cancer (cT1cN0M0, cStage I) and underwent total mastectomy and sentinel lymph node biopsy. Lymph node metastasis was recognized and axillary dissection (Level II) was added. The pathology revealed invasive lobular carcinoma, 16×13 mm, ly(+), v(±), histological grade : 1, n2, hormone receptor positive, HER2 negative, and pStage IIIA. We recommended adjuvant chemotherapy, but she did not desire. She started oral administration of an aromatase inhibitor and radiation therapy. When DFI was 3 years and 1 month, an examination was carried out because the increase in CEA value, urination pain and hematuria were recognized. A contrast-enhanced CT scan revealed a mass extending from the bladder to the right ovary. We suspected ovarian invasion of bladder cancer. She underwent a bladder biopsy. The result was bladder metastasis of breast cancer. Endocrine therapy was continued, and radiotherapy was performed. Later, we introduced chemotherapy, but it was withdrawn with her request. She wished BSC. She developed dysuria 1 year and 3 months and died 1 year and 4 months after the diagnosis of bladder metastasis.