Resection of Liver Metastasis from Gastric Neuroendocrine Cell Carcinoma—Report of a Case—

Abstract

The case of a 61-year-old man who developed neuroendocrine cell carcinoma of the stomach is presented. Contrast-enhanced computed tomography (CT) showed no distant metastasis. Distal gastrectomy with D2 lymph node resection was performed based on the diagnosis of gastric cancer [T4a(SE)N2M0 ; cStage III]. The specimen showed poorly differentiated adenocarcinoma of the stomach. The patient's postoperative course was uneventful, and S-1 was started as adjuvant chemotherapy. However, CT showed metastasis in the right lobe of the liver 3 months later. Right lobectomy of the liver was then performed, and the specimen showed neuroendocrine cell adenocarcinoma of the stomach and liver. The patient's postoperative course was uneventful, and CPT-11 and CDDP were started as postoperative chemotherapy. Neuroendocrine cell adenocarcinoma of the stomach is relatively rare, has a poor prognosis, and requires multidisciplinary therapy. This case is reported in the context of the relevant literature.