A Case of Transeverse Colon Carcinoma with Rhabdoid Features Progressed Rapidly

Abstract

Malignant rhabdoid tumor (MRT) is a tumor arisen from the kidney in infants and toddlers and has a poor prognosis. It is rarely identified as the presence of rhabdoid-like cells in adenocarcinoma of the digestive organs (neoplasm with rhabdoid features). We have experienced a case of MRT of the transverse colon. The patient was an 87-year-old man who presented with abdominal distention and tested positive for fecal occult blood. A colonoscopy revealed a tumorous lesion completely encircling the transverse colon at the hepatic flexure. It was diagnosed as poorly differentiated adenocarcinoma by a biopsy. An abdominal CT scan confirmed regional lymph node swelling. We performed partial resection of the transverse colon with a diagnosis of transverse colon carcinoma. Histopathology revealed a predominance of undifferentiated rhabdoid cells (positive for both AE1/3 and vimentin) where large oval shaped nuclei distributed unevenly. The histopathological diagnosis was undifferentiated carcinoma with rhabdoid features, Type 2, 8.5 × 6.6 cm, SS, Ly1a, V1c. As it is believed that the prognosis of cancer presenting with rhabdoid feature is extremely poor, in this case, the patient's general condition rapidly aggravated and he died 40^th postoperative day.