A Patient with Primary Adenosquamous Carcinoma of the Liver Surviving for 6 Years after R0 Resection and GEM/S-1 Therapy

Abstract

A 67-year-old man presented at a local clinic complaining of epigastric discomfort. On detailed examination, intrahepatic bile duct cancer was diagnosed, and left hepatic lobectomy and lymph node resection were performed in October 2015. On histopathological examination, a pathological diagnosis of primary adenosquamous carcinoma of the liver with lymph node metastasis was made, and GEM/S-1 (GS) therapy was started as postoperative adjuvant chemotherapy. This was suspended 5 months postoperatively due to the progression of anemia, but 1 year postoperatively, a recurrent lesion appeared near the anastomosis site. After GS therapy was restarted, the recurrent lesion became unclear. Today, 6 years postoperatively, the patient is surviving with no sign of recurrence.