2022 Volume 83 Issue 7 Pages 1283-1289
An 88-year-old woman was being followed at another hospital after surgery for cancer of the cecum and descending colon in 2013. In 2020, she experienced epigastric pain, and since upper gastrointestinal endoscopy showed gastric cancer, she was referred to our department. A mesenteric cyst that had enlarged compared with 2016 was also present, and this was suspected to be a neoplastic lesion ; therefore, distal gastrectomy and mesenteric cyst removal were conducted in the same procedure. The pathological diagnoses were gastric cancer (pT3N2M0, Lylc, V1b, pStage IIIA) and mesenteric liposarcoma (S100 positive, SMA weakly positive, highly differentiated or dedifferentiated). Liposarcoma occurs most frequently in the limbs and retroperitoneum, and primary mesenteric liposarcoma is rare. There has been no previously reported case of its occurrence with gastric cancer as synchronous double cancer. The case of a patient with synchronous gastric cancer and mesenteric liposarcoma monitored for approximately 4 years is reported with a discussion of the literature.