Gastrointestinal AL Amyloidosis Associated with Intussusception—A Case Report—

Abstract

AL amyloidosis associated with ileocecal intussusception is a rare condition. One such case is reported along with a literature review. A 91-year-old man was admitted to our hospital with complaints of general malaise and right lower abdominal pain. Abdominal computed tomography showed a target sign around the ascending colon. Colonoscopic examination showed an elevated lesion at the ileocecal region, which invaginated into the ascending colon. The biopsy results suggested amyloidosis, but the possibility of malignancy could not be ruled out, and surgery was selected to relieve the intestinal obstruction. A laparoscopic right hemicolectomy was performed. A camera port was inserted in the umbilical region, for a total of five ports. A small 4.0-cm incision was made at the umbilical region, and reconstruction was performed by functional end-to-end anastomosis. Grossly, the resected specimen showed tumor-like thickening, 4.0 cm in diameter, from the ileum to Bauhin's valve. Histopathological findings showed amyloid deposition in the submucosa, leading to the diagnosis of amyloidosis. The amyloid was immunohistochemically typed AL. The patient was discharged on postoperative day 9.