A Rare Case of Juvenile Papillomatosis of the Breast

Abstract

A 33-year-old Latin American woman, with a family history of breast cancer in her first cousin, initially presented with a lump in her right breast that had been present for 1 month. Ultrasonography revealed an 8-cm mass under the right nipple. The core needle biopsy performed by the previous doctor did not indicate malignancy. Due to the large size of the tumor, the patient was subsequently referred to our institution for surgical excision. Imaging showed a 75-mm tumor with numerous cystic lesions. Although the review of the specimen at our institution could not definitively rule out ductal carcinoma in situ, preoperative imaging did not provide any evidence of malignancy. The patient underwent tumor excision, and the pathological diagnosis was juvenile papillomatosis (JP). JP of the breast is a relatively rare disease and cases in the Asian population are rarely reported. Complete resection of the tumor is the first choice for the treatment of JP, and systemic treatment is generally not required. However, regular follow-up care is necessary because JP, especially in conjunction with a positive family history, might be a risk factor for developing breast cancer.