A Case of Breast Cancer Associated with Infarcted Necrosis following Needle Biopsy

Abstract

A 68-year-old woman was being followed up for amorphous grouped calcification of the left breast in our hospital for 10 years. During the annual checkup, a mammogram detected a new circumscribed mass in the upper-inner quadrant of the left breast, which was estimated as category 3. Subsequent ultrasound examination revealed a 16 mm well-defined and irregular mass in the same area. Core needle biopsy confirmed the presence of invasive ductal carcinoma, characterized as hormone receptor positive and HER2 negative. Partial mastectomy and sentinel lymph node biopsy were carried out for left breast cancer (cT1N0M0, stage I). Histopathological examination revealed no viable cancer cells, and only a nodular lesion with necrosis surrounded by granulation was observed. The diagnosis pointed to tumor necrosis. Ultrasound showed no residual lesion in the breast post surgery. Postoperative treatments included radiation therapy and endocrine therapy for 5 years, and there has been no recurrence 9 years postoperatively.