A Case of Repeated Pancreatectomy of a Recurrent Pancreatic Metastases Five Years after the First Resection for Pancreatic Metastasis of Renal Cell Carcinoma

Abstract

A 73-year-old man underwent central pancreatectomy for a mass in the head of the pancreas that appeared seven years after left nephrectomy for clear cell renal cell carcinoma, and the histopathological diagnosis was pancreatic metastasis of clear cell renal cell carcinoma. Five years after central pancreatectomy, two masses were identified in the residual pancreatic tail. Abdominal contrast-enhanced computed tomography showed 11-mm and 16-mm well-circumscribed hypervascular masses in the residual pancreatic tail. Endoscopic ultrasound also revealed both two well-circumscribed nodules. From the clinical course, recurrent residual pancreatic metastases of renal cancer was diagnosed, and distal pancreatectomy with splenectomy was performed. Histopathologically, both lesions were consistent with metastases of clear cell renal cell carcinoma. One year and four months after the last surgery, the patient is alive without recurrence.

Pancreatic metastasis of renal cell carcinoma is rather common in metastasis to the pancreas alone with no metastasis elsewhere, but few cases of repeated pancreatic metastases have been reported. Herein, a case of repeated pancreatectomy of recurrent pancreatic metastases from renal cell carcinoma is reported.