2025 Volume 86 Issue 6 Pages 818-822
A 72-year-old man had previously undergone distal pancreatectomy and splenectomy for a G2 pancreatic neuroendocrine tumor (pNET). Eleven years after surgery, follow-up computed tomography showed a mass lesion, 3.8 cm in diameter, in S8 of the liver, which was suspected to be recurrence of hepatic metastases from pNET. Laparoscopic hepatic S8 segmentectomy was performed for the lesion. The patient was discharged without any postoperative complications on the 8th postoperative day. The pathological examination showed NET G2 that was almost identical to that of the previous pancreatic surgery. Hematological recurrence of pNETs is well known even after curable resection. However, it has been reported that such recurrences commonly occurred less than 10 years after surgery. A rare case with a late hepatic recurrence of pNET that was successfully resected by laparoscopic surgery is reported.