THE JOURNAL OF JAPAN SOCIETY FOR CLINICAL ANESTHESIA
Online ISSN : 1349-9149
Print ISSN : 0285-4945
ISSN-L : 0285-4945
Case Reports
Bleeding Tendency? Clotting Tendency? Similar Preoperative Abnormal Laboratory Values in Two Cases Resulted in Opposite Coagulopathy
Tomoaki HIGASHIZAWAHaruyuki YUASAToru SHIRAIKatsutoshi WAKITA
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2004 Volume 24 Issue 2 Pages 95-98

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Abstract
A seventy-year-old male (case 1) and an eighty-year-old male (case 2) who were scheduled for transurethral resection of the prostate (TUR-P) under spinal anesthesia. They showed the results of preoperative laboratory examinations within normal-range except the prolonged activated partial thromboplastin time (aPTT). Case 1 did not show a bleeding disorder in daily practical findings, and he was diagnosed with antiphospholipid antibody syndrome upon a more detailed examination. Case 2 showed a bleeding disorder and he was diagnosed with von Willebrand disease upon a more detailed examination before the operations. In both cases, the anesthesia and the operation were uneventful. In case 2, 33 IU · kg-1 of clotting factor VIII was preoperatively intravenously administered. However, in case 1, embolism of the retinal central vein occurred 4 weeks after the operation. Abnormal prolonged aPTT values indicated both a clotting tendency and a bleeding tendency.
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© 2004 by The Japan Society for Clinical Anesthesia
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