Abstract
We prospectively examined awareness during general anesthesia over the past two years. We discovered two cases of awareness with recall during anesthesia in 1,872 patients who underwent general anesthesia. Both patients were in hemorrhagic shock preoperatively, and had intraoperative BIS values less than 60. The amount of anesthetic administered during operation was insufficient, because their hemodynamic parameters were unstable. Monitoring of BIS does not appear to be reliable for detection of awareness, when intraoperative administration of analgesics is insufficient.