2006 Volume 26 Issue 7 Pages 674-678
Travelmin® has been widely used for the prevention or treatment of motion sickness. We studied the prophylactic effect of Travelmin® on PONV.
One hundred twenty adult patients undergoing elective orthopedic surgery were enrolled in this randomized study. All patients had a laryngeal mask airway inserted after receiving propofol. Anesthesia was maintained with sevoflurane, nitrous oxide in oxygen and intravenous pentazocine. Sixty patients allocated to the treatment group received 1ml of Travelmin® subcutaneously at the start of wound closure. We evaluated the incidence of PONV during the following 24 hours.
The patients' demographics were similar between the two groups. The incidence of PONV was significantly lower in the Travelmin® group than in the control group (10% vs 38 %) . PONV was triggered by motion in 38%.
Travelmin® is less expensive than other antiemetics, with few adverse effects recorded. We conclude that Travelmin® is a useful prophylactic for PONV.
