THE JOURNAL OF JAPAN SOCIETY FOR CLINICAL ANESTHESIA
Online ISSN : 1349-9149
Print ISSN : 0285-4945
ISSN-L : 0285-4945
Journal Symposium (4)
Basic and Clinical Pharmacology of Ropivacaine
Ken YAMAMOTO
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JOURNAL FREE ACCESS

2009 Volume 29 Issue 4 Pages 509-518

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Abstract
  Ropivacaine is a new long-acting local anesthetic produced through modern technology to separate pure isomers. Although ropivacaine is supposed to have better differentiation in sensory/motor blockade, clinical studies do not necessarily support the differential effect. The relevant advantage of ropivacaine over racemic bupivacaine is reduced potential for systemic toxicity. Its better cardiotoxic profile is an especially important advantage when using techniques with a potential for high plasma concentrations.
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© 2009 by The Japan Society for Clinical Anesthesia
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